Research Articles1. Zheng, Di; Tao, Jing; Jiang, Liping; Zhang, Xinyue; He, Huibin; Shen, Xiaoxue; Sang,Yutao; Liu, Yunen*; Yang, Zhenzhong*; Nie, Zhihong*. J. Am. Chem. Soc., 2025, 147, 998-1007.Designing artificial enzymes for in vivo catalysis presents a great challenge due to biomacromolecule contamination, poor biodistribution, and insufficient substrate interaction. Herein, we developed s...